New NIH funding on Prader-Willi syndrome
/We’re excited that we have been awarded an R01 from NINDS to investigate the molecular consequences of snoRNA deletion in Prader-Willi syndrome.
Read MoreWe’re excited that we have been awarded an R01 from NINDS to investigate the molecular consequences of snoRNA deletion in Prader-Willi syndrome.
Read MoreWe’re excited to share that Christian Overbeck (Whipple Lab Intern 2019) has matched into the Internal Medicine/Global Health Residency Program at Stanford Health Care. Congratulations, Christian—we’re cheering you on!
Read MoreBongmin (Min) Bae, a postdoctoral researcher in the Whipple lab, has been awarded a new postdoctoral fellowship from the American Heart Association. The two-year award will support Bae’s research on how epigenetic mechanisms regulate gene expression in the mammalian brain.
Read MoreOur new preprint is now live on bioRxiv! We uncover how maternal and paternal genomes adopt distinct 3D chromatin structures across multiple imprinted domains in the mouse brain, and show that these architectures can work together with cis-acting long non-coding RNAs to shape allele-specific gene expression.
Read MoreWe invite all current G1 students in a HILS (Harvard Integrative Life Sciences) program to join us for an open house on November 4 at 6:15 PM. Dinner provided. Email for additional details.
Read MoreDina was selected as a finalist amongst a competitive pool of applicants and presented a five-minute lightning talk in front of 250+ participants in the Harvard research community.
Read MoreOur proposal “Decoding Genomic Imprinting for Therapeutic Innovation,” developed together with lab member Dina Aljogol, has been selected for funding by the Milton Fund from Harvard University. We are grateful to the Harvard community for supporting this work.
Read MoreCongratulations to two Whipple lab trainees, Courtney and Jen, for winning “the most beautiful experiment of the year” in the Harvard MCB Department! We also thank Min for her contributions to the original idea for the experiment; it was a truly collaborative effort. Courtney gave a talk at the departmental retreat highlighting this work.
Read MoreOur latest study introduces a powerful chimeric eCLIP approach to map snoRNA-target RNA interactions across human and mouse cells. By analyzing binding partners of both core and accessory snoRNA-binding proteins, we uncover dozens of novel snoRNA interactions — shedding new light on their roles in RNA processing and modification. Read the full paper here.
Read MoreThe Whipple Lab is excited to have Fahmida Afreen join as an undergraduate researcher. Fahmida is a freshman at Harvard College intending to double concentrate in Applied Math and Molecular and Cellular Biology.
Dina is a postdoctoral fellow interested in the molecular mechanisms of imprinted gene regulation. Before joining Harvard, she completed her PhD at Hamad Bin Khalifa University, where she studied chromatin organization and long-range promoter contacts in autism spectrum disorders.
Read MoreThe Whipple Lab welcomes MCO graduate student Isra Galicia Silva to the lab. She received her B.S. in Biochemistry and Microbiology from the Universidad del Valle de Guatemala and completed a Post-Baccalaureate at the University of Pennsylvania, where she worked with the J-Rad Lab on the interplay between metabolism, circadian rhythms, and cellular maturation.
Read MoreCongratulations to Min Bae on receiving a postdoctoral fellowship award to further study how the Mest-Copg2 ICR achieves long-range regulation.
Read MoreThe Whipple Lab welcomes our newest member, Katherine Gu. Katherine joins us as a research assistant. She received her B.A. in Biochemistry and Chemical Biology from Vanderbilt University. Outside of lab, she enjoys working out, hiking, and trying restaurants in the Boston area.
Read MoreCongratulations to Carlie McGrath Tydings who will be joining the Greenleaf Lab at the Stanford Department of Genetics in July, as a research assistant.
Read MoreCongratulations to Aditya for graduating from Harvard! He will be attending graduate school at MIT in the fall.
Read MoreLily will be part of Harvard’s Program for Research Science and Engineering (PRISE) this summer. Her project with the Whipple lab will involve observing hallmarks of nucleolar stress and the role of small nucleoar RNAs on neuronal function.
Read MoreCongratulations to Research Assistant Jen Yi! This fall, Jen will begin graduate school in the Harvard MCO program.
Read MoreDebaleena Kar has joined the Whipple lab as a Postdoctoral Fellow. Her research focuses on the role of snoRNA in translation.
Read More