DNA folding choices made in stem cells determines how genes are expressed in the brain

DNA folding choices made in stem cells determines how genes are expressed in the brain

A new study led by Daniel Loftus of the Whipple Lab has found that differences in maternal and paternal genomes in embryonic stem cells shape gene expression in neurons. The study, which appears in the latest issue of the journal Genes & Development, delves into the 3D structure of a genome region called Peg13-Kcnk9.

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