Our paper is now published in Nature Communications! We uncover how maternal and paternal genomes adopt distinct 3D chromatin structures across multiple imprinted domains in the mouse brain, and show how these architectures work together with cis-acting long non-coding RNAs and distal regulatory elements to shape allele-specific gene expression.
Read MoreCourtney successfully defends her PhD!
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Congratulations to Courtney on earning her PhD from the Harvard Program in Neuroscience! Over the years, she has grown into a rigorous scientist, aspiring bioinformatician, and thoughtful mentor. We can’t wait to see what she accomplishes next—look out world!
Read MoreWe're Hiring: Research Assistant I→
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The Research Assistant will contribute to an individual research project within the lab’s broader program while also supporting laboratory operations. This position is ideal for candidates seeking significant hands-on research experience and mentorship in preparation for graduate training.
See full job description and submit application here https://us.smrtr.io/4KVbp
Read MoreNow Recruiting: Postdoctoral Fellows in RNA Biology
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We are recruiting postdoctoral fellows to study the molecular functions of orphan snoRNAs, a large and poorly understood class of non-coding RNAs. Join us to uncover new mechanisms of RNA-mediated gene regulation in the brain. Read more about the positions here.
Read MoreNew NIH funding on Prader-Willi syndrome
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We’re excited that we have been awarded an R01 from NINDS to investigate the molecular consequences of snoRNA deletion in Prader-Willi syndrome.
Read MoreLab alumnus Christian Overbeck achieves residency match at Stanford
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We’re excited to share that Christian Overbeck (Whipple Lab Intern 2019) has matched into the Internal Medicine/Global Health Residency Program at Stanford Health Care. Congratulations, Christian—we’re cheering you on!
Read MoreBongmin Bae awarded new postdoc fellowship→
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Bongmin (Min) Bae, a postdoctoral researcher in the Whipple lab, has been awarded a new postdoctoral fellowship from the American Heart Association. The two-year award will support Bae’s research on how epigenetic mechanisms regulate gene expression in the mammalian brain.
Read MoreNew Publication Alert→
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Our new preprint is now live on bioRxiv! We uncover how maternal and paternal genomes adopt distinct 3D chromatin structures across multiple imprinted domains in the mouse brain, and show that these architectures can work together with cis-acting long non-coding RNAs to shape allele-specific gene expression.
Read MoreOpen house for G1 students
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We invite all current G1 students in a HILS (Harvard Integrative Life Sciences) program to join us for an open house on November 4 at 6:15 PM. Dinner provided. Email for additional details.
Read MoreDina Aljogol competes at the Zymo Biofestival
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Dina was selected as a finalist amongst a competitive pool of applicants and presented a five-minute lightning talk in front of 250+ participants in the Harvard research community.
Read MoreWhipple lab receives funding from the Milton Fund
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Our proposal “Decoding Genomic Imprinting for Therapeutic Innovation,” developed together with lab member Dina Aljogol, has been selected for funding by the Milton Fund from Harvard University. We are grateful to the Harvard community for supporting this work.
Read MoreCourtney Whilden and Jen Yi win Meselson Prize
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Congratulations to two Whipple lab trainees, Courtney and Jen, for winning “the most beautiful experiment of the year” in the Harvard MCB Department! We also thank Min for her contributions to the original idea for the experiment; it was a truly collaborative effort. Courtney gave a talk at the departmental retreat highlighting this work.
Read MoreNew Publication Alert→
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Our latest study introduces a powerful chimeric eCLIP approach to map snoRNA-target RNA interactions across human and mouse cells. By analyzing binding partners of both core and accessory snoRNA-binding proteins, we uncover dozens of novel snoRNA interactions — shedding new light on their roles in RNA processing and modification. Read the full paper here.
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Welcome Fahmida Afreen
/The Whipple Lab is excited to have Fahmida Afreen join as an undergraduate researcher. Fahmida is a freshman at Harvard College intending to double concentrate in Applied Math and Molecular and Cellular Biology.
Welcome to Dina Aljogol
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Dina is a postdoctoral fellow interested in the molecular mechanisms of imprinted gene regulation. Before joining Harvard, she completed her PhD at Hamad Bin Khalifa University, where she studied chromatin organization and long-range promoter contacts in autism spectrum disorders.
Read MoreWelcome Isra Galicia Silva
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The Whipple Lab welcomes MCO graduate student Isra Galicia Silva to the lab. She received her B.S. in Biochemistry and Microbiology from the Universidad del Valle de Guatemala and completed a Post-Baccalaureate at the University of Pennsylvania, where she worked with the J-Rad Lab on the interplay between metabolism, circadian rhythms, and cellular maturation.
Read MoreMin Bae receives F32 fellowship→
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Congratulations to Min Bae on receiving a postdoctoral fellowship award to further study how the Mest-Copg2 ICR achieves long-range regulation.
Read MoreWelcome Katherine Gu
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The Whipple Lab welcomes our newest member, Katherine Gu. Katherine joins us as a research assistant. She received her B.A. in Biochemistry and Chemical Biology from Vanderbilt University. Outside of lab, she enjoys working out, hiking, and trying restaurants in the Boston area.
Read MoreCarlie to join Stanford Greenleaf Lab
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Congratulations to Carlie McGrath Tydings who will be joining the Greenleaf Lab at the Stanford Department of Genetics in July, as a research assistant.
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