Allelic chromatin structure is a pervasive feature of imprinted domains and functions cooperatively with cis-acting long non-coding RNAs. Bae B*, Gu K, Loftus D, Whipple AJ. bioRxiv, 2025. bioRxiv
Mapping snoRNA-target RNA interactions in an RNA-binding protein-dependent manner with chimeric eCLIP. Song Z*, Bae B*, Schnabl S, Yuan F, De Zoysa T, Akinyi MV, Le Roux CA, Choquet K, Whipple AJ#, Van Nostrand EL#. Genome Biol, 2025. PubMed
Allelic chromatin structure primes imprinted expression of Kcnk9 during neurogenesis. Loftus D, Bae B, Whilden CM, Whipple AJ. Genes & Development, 2023. PubMed
Featured in: Folding makes an imprint. Stricker F. Genes & Development, 37:779-780. PubMed
Imprinted maternally-expressed microRNAs antagonize paternally-driven gene programs in neurons. Whipple AJ, Breton-Provencher V, Jacobs HN, Chitta UK, Sur M, Sharp PA. Molecular Cell, 2020. PubMed
Featured in: Imprinted small RNAs unraveled: Maternal microRNAs antagonize a paternal-genome-driven gene expression network. Ghousein A & Feil R. Molecular Cell, 2020. PubMed
Disrupted neuronal maturation in Angelman syndrome-derived induced pluripotent stem cells. Fink JJ, Robinson TM, Germain ND, Sirois CL, Bolduc KA, Ward AJ, Rigo F, Chamberlain SJ, & Levine ES. Nature Commun, 2017. PubMed
The antisense transcript SMN-AS1 regulates SMN expression and is a novel therapeutic target for spinal muscular atrophy. d’Ydewalle C, Ramos DM, Pyles NJ, Ng SY, Gorz M, Pilato CM, King K, Kong L, Ward AJ, Rubin LL, Rigo F, Bennett CF, & Sumner CJ. Neuron, 2017. PubMed
Towards a therapy for Angelman syndrome by targeting a long non-coding RNA. Meng L*, Ward AJ*, Chun S, Bennett CF, Beaudet AL, & Rigo F. Nature, 2015. PubMed
Featured in: Neurodevelopmental disorders: Unmuting Ube3a in mice alleviates Angelman syndrome. Malkki H. Nature Review Neurology, 2015. PubMed